Health and Fitness

Is zolpidem a good sleeping pill? What are the benefits?

Zolpidem Tartarate- The best sleeping pill

It is taken by patients who are experiencing insomnia. Insomnia is a state of mind in which the person is unable to sleep or wakes up in the night after just a short nap and fails to put oneself to sleep again. Taking zolpidem will not take away your sleep disturbances by one dose only, but rather it will reduce the number of times you wake up in the middle of the night at first and then will take away all your insomnia by the fourteenth day.

Oral Use of Zolpidem

The medicine can be taken empty stomach or can be taken with food too. It should be taken once a day. One should take it before sleeping only. If you have a working day ahead, it is highly advised that you take this medicine at night and not during the day. Otherwise, it will make you so drowsy that you won’t be able to do your work timely. It will also make you lose your focus.

Availability of Tablets

The oral tablets of Zolpidem come both as a brand name as well as generic. Its brand names include; Ambien which is the immediate-release tablet, Ambien Cr which is the extended-release tablet, Edluar, and Intermezzo which are both sublingual tablets. Zolpidem also comes as an oral spray that can be sprayed in the mouth of a patient. The tablets have been designed in a way so that a person can remain in a sleeping state for a normal time duration. It can also help a person fall asleep who was unable to sleep before.

The immediate-release tablet will release its contents right away. The extended-release will take some time to release it which the sublingual drug is designed to dissolve under your tongue. The sublingual tablets are only used if you have fallen asleep once and wake up in the middle of the night. It is a low-dose tablet having a concentration of about 1.75mg to 3.5mg. It will put you to sleep in the remaining part of the night.

Generic Vs Brand-Name

Generic drugs are available in the market at a lower price than the brand name. That is why if a person has knowledge about the generic name of a drug, he can buy that from the market without having to pay extra for the brand name version. However, the brand-name version always comes with quality and guarantees effectiveness.

Zolpidem and GABA

The working mechanism of zolpidem includes increasing the activity of GABA in the brain. GABA is a neurotransmitter that reduces the activity in your brain and will help you fall asleep in a matter of minutes. In insomnia, the production of GABA is reduced in your brain. That is why a person is unable to relax and feel the need of falling asleep, though the tiredness is ever lingering.

Things to know about Zolpidem

Though the medicine is safe medically, just like every other medicine, it also has some mild effects too.  The common side effects include drowsiness, dizziness, diarrhea, chest pain, dry mouth and mild headaches. Some patients also experience palpitations like irregular heartbeat, a faster pace of heart, some level of grogginess as well as muscle pain.

The side effects are not severe at all if the medicine is taken as per the guidelines. However, for maximum results, a person must be punctual in taking his zolpidem tablets. The serious side effects include:

1.  Allergic Reactions

There is swelling on your face or tongue. This can lead to breathing troubles.

2.  Depression

Overdosing of medication can sometimes lead to suicidal thoughts. You can also experience a loss of interest in activities that occur in daily life. If this is not treated, it will lead to the development of feelings like worthlessness or feelings of guilt. As a result, the person feels drained all the time and there is a consistent lack of energy in the individual. Most of the time, depression causes either weight loss or weight gain.

3.  Abnormal Behavior or Thoughts

There are some behavioral changes that can develop when a person is having withdrawal symptoms like agitation, hallucinations, or being more outgoing than a normal routine. Some people even start doing activities while they are asleep like talking on the phone, eating food as well as driving.

Over-the-counter Sleeping Pills

Before a person starts taking on zolpidem, you should tell your doctor about all the medication that you take including over-the-counter sleeping pills. Similarly, this is the case if you are taking herbs, vitamins as well as any supplements. This way, potential interaction can be avoided.

Combinational Therapy

Sometimes, zolpidem can have adverse side effects if it is taken with chlorpromazine as well as imipramine.  A person will experience more drowsiness as well as sedation if he is on such drugs. If you are taking zolpidem with other medicines, to produce the same effect, zolpidem’s amount of intake will have to be increased.

This includes:

  1. Antibiotics like erythromycin as well as clarithromycin
  2. Anti-fungals like itraconazole, ketozonazole as well as voriconazole

Reaction Time Warning

If you are already on zolpidem and still do not get a good night’s sleep then you may be experiencing a condition called a slower reaction time. This leads to decreased awareness ability. If you are taking sublingual tablets you should drive at all or indulge in activities that require alertness. You should at least get more than four hours of sleep so that you don’t feel much drowsy.

Maximum Dose For Zolpidem

The starting dose will be 5mg for women and 10mg for men. This is due to the difference in their muscle mass as well as metabolism. The dose must be taken at least 6 hours before going to bed. The dose can be increased or decreased as per the patient’s evaluation. The maximum dose that has been given till now is 10mg per day. However, it is least preferred by doctors.


Zolpidem has a great market reputation and is doing so well for the patients overall. It is a drug that is recommended by doctor and one must not think twice about purchasing it!

Related Articles

Leave a Reply

Your email address will not be published.

Back to top button